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- Downstream Processing
Hydrophobic Interaction Chromatography: Effects of Mixed Electrolytes on Protein Separations
BPI Contributor
January 1, 2014
1 Min Read
Sponsored by Tosoh Bioscience
For HIC separations, parameters other than resin surface modifications can be employed to enhance performance. This application note addresses the electrolyte composition of the mobile phase as one parameter responsible for protein adsorption and desorption. The results presented illustrate the benefits regarding capacity and selectivity in HIC of often neglected salts and their mixtures.
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