Bioreactors

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Gene Therapies
A Scale-Up/-Down Platform for Fast-Paced Upstream Process Development of rAAV-Based Gene TherapiesA Scale-Up/-Down Platform for Fast-Paced Upstream Process Development of rAAV-Based Gene Therapies

+5
byTereza Pavlištová, Maria João Alves Correiaand 5 more
Oct 17, 2024
mass-transfer steps
Bioreactors
Lessons in Bioreactor Scale-Up, Part 4: Physiochemical Factors Affecting Oxygen Transfer and the Volumetric Mass-Transfer Coefficient in Stirred TanksLessons in Bioreactor Scale-Up, Part 4: Physiochemical Factors Affecting Oxygen Transfer and the Volumetric Mass-Transfer Coefficient in Stirred Tanks
byMuhammad Arshad Chaudhry
Oct 15, 2024
bioreactor
Bioreactors
Lessons in Bioreactor Scale-Up: Part 3 — Experimental Determination and Application of Oxygen Mass- Transfer Rate, Mass-Transfer Coefficient, and Oxygen-Uptake RateLessons in Bioreactor Scale-Up — Part 3: Experimental Determination and Application of Oxygen Mass- Transfer Rate, Mass-Transfer Coefficient, and Oxygen-Uptake Rate
byMuhammad Arshad Chaudhry
Sep 9, 2024
ATE recap
Sponsored Content
Optimizing Perfusion Parameters for CAR-T Cells: Intensified Production in the Ambr 250 High-Throughput Bioreactor (Webcast Recap)Optimizing Perfusion Parameters for CAR-T Cells: Intensified Production in the Ambr 250 High-Throughput Bioreactor (Webcast Recap)
byJulia Hengst
Sep 1, 2024
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Bioreactors
BPI Theater Interview: Nick Jackowetz, Senior Vice President and Principal Scientist, Hydrosome LabsBPI Theater Interview: Nick Jackowetz, Senior Vice President and Principal Scientist, Hydrosome Labs
byBPI Editors
Jul 31, 2024
turbulent flow image
Bioreactors
Lessons in Bioreactor Scale-Up, Part 2: A Refresher on Fluid Flow and MixingLessons in Bioreactor Scale-Up, Part 2: A Refresher on Fluid Flow and Mixing
byMuhammad Arshad Chaudhry
Jun 12, 2024
Bioreactor
Bioreactors
Lessons in Bioreactor Scale-Up: Part 1 — Exploring Introductory Principles
Lessons in Bioreactor Scale-Up: Part 1 — Exploring Introductory Principles
Feb 7, 2024
byMuhammad Arshad Chaudhry
Bioreactors
Characterizing Oxygen Mass Transfer and Shear During Cell Culture: Calculating the Maximum Cell Density Supported By a 20,000-Liter Stirred-Tank Bioreactor
Characterizing Oxygen Mass Transfer and Shear During Cell Culture: Calculating the Maximum Cell Density Supported By a 20,000-Liter Stirred-Tank Bioreactor
Feb 6, 2024
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byNaveenganesh Muralidharan, Emma Bolducand 1 more
Cell Culture Media Fingerprinting: A Three-Tiered Approach
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Cell Culture Media Fingerprinting: A Three-Tiered Approach
Cell Culture Media Fingerprinting: A Three-Tiered Approach
Sep 19, 2023
+12
byGitanjali Talreja, Amandine Calvetand 12 more
Xeno-free T cell Expansions in PBS Mini Vertical-Wheel® Bioreactor Using CellGenix® reagents
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Xeno-free T cell Expansions in PBS Mini Vertical-Wheel® Bioreactor Using CellGenix® reagents
Xeno-free T cell Expansions in PBS Mini Vertical-Wheel® Bioreactor Using CellGenix® reagents
Jun 29, 2023
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1 Min Read
byBPI Contributor
BPI Europe Interview: Gareth Jones, PhenomeX
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BPI Europe Interview: Gareth Jones, PhenomeX
BPI Europe Interview: Gareth Jones, PhenomeX
Jun 21, 2023
byBPI Staff
BPI Europe Interview: Christian Witz, Sim Vantage
Sponsored Content
BPI Europe Interview: Christian Witz, Sim Vantage
BPI Europe Interview: Christian Witz, Sim Vantage
Jun 21, 2023
byBPI Staff
Shear-Proof Design Space: Scaling Stirred-Tank Bioreactors for Cell Culture Processes
Bioreactors
Shear-Proof Design Space: Scaling Stirred-Tank Bioreactors for Cell Culture Processes
Shear-Proof Design Space: Scaling Stirred-Tank Bioreactors for Cell Culture Processes
Feb 9, 2023
byNaveenganesh Muralidharan
Cell-Expansion Benefits Using Hollow-Fiber Bioreactor Technology logo in a gray background | Cell-Expansion Benefits Using Hollow-Fiber Bioreactor Technology
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Cell-Expansion Benefits Using Hollow-Fiber Bioreactor Technology
Cell-Expansion Benefits Using Hollow-Fiber Bioreactor Technology
Feb 9, 2023
byStuart Gibb
Raman Spectrometric PAT Models: Successful Transfer from Minibioreactors to Larger-Scale, Stirred-Tank Bioreactors
PAT
Raman Spectrometric PAT Models: Successful Transfer from Minibioreactors to Larger-Scale, Stirred-Tank Bioreactors
Raman Spectrometric PAT Models: Successful Transfer from Minibioreactors to Larger-Scale, Stirred-Tank Bioreactors
Sep 28, 2022
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byJens Classen, Matthaeus Langerand 2 more
Analytical Tools for Improving Up- and Downstream AAV Process Development logo in a gray background | Analytical Tools for Improving Up- and Downstream AAV Process Development
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Analytical Tools for Improving Up- and Downstream AAV Process Development
Analytical Tools for Improving Up- and Downstream AAV Process Development
Sep 28, 2022
byIvana Petrović Koshmak
Hardware, Software, and Wetware: 20 Years of Advancements in Biopharmaceutical Production, Part 1
Bioreactors
Hardware, Software, and Wetware: 20 Years of Advancements in Biopharmaceutical Production, Part 1
Hardware, Software, and Wetware: 20 Years of Advancements in Biopharmaceutical Production, Part 1
Aug 22, 2022
byYuval Shimoni, Cheryl Scott
eBook: Factors Affecting Scalability of Cell Therapies
Cell Therapies
eBook: Factors Affecting Scalability of Cell Therapies
eBook: Factors Affecting Scalability of Cell Therapies
Jul 25, 2022
+1
byBrian Gazaille, Miguel Forteand 1 more
Pressure Vessels for Biomanufacturing: Basic Considerations for Cleaning and Process Compatibility
Bioreactors
Pressure Vessels for Biomanufacturing: Basic Considerations for Cleaning and Process Compatibility
Pressure Vessels for Biomanufacturing: Basic Considerations for Cleaning and Process Compatibility
Jun 21, 2022
bySuthan Rupesh
High-Yield Production of rAd26-S for Sputnik V Vaccine Component I: An Optimized Process in a Scalable Shaken Bioreactor
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High-Yield Production of rAd26-S for Sputnik V Vaccine Component I: An Optimized Process in a Scalable Shaken Bioreactor
High-Yield Production of rAd26-S for Sputnik V Vaccine Component I: An Optimized Process in a Scalable Shaken Bioreactor
Dec 21, 2021
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byKatharina Vogdt, Leander Johnand 7 more
Strategizing Scale-Up and Scale-Out for Cell Therapy Production
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Strategizing Scale-Up and Scale-Out for Cell Therapy Production
Strategizing Scale-Up and Scale-Out for Cell Therapy Production
Sep 30, 2021
byChris Suarez
Ask the Expert: Facilitating Process Development Using a Microfluidic Perfusion Bioreactor logo in a gray background | Ask the Expert: Facilitating Process Development Using a Microfluidic Perfusion Bioreactor
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Ask the Expert: Facilitating Process Development Using a Microfluidic Perfusion Bioreactor
Ask the Expert: Facilitating Process Development Using a Microfluidic Perfusion Bioreactor
Sep 29, 2021
byBPI Contributor
High-Yield AAV Viral Vector Production in Corning Ascent Fixed-Bed Reactor System
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High-Yield AAV Viral Vector Production in Corning Ascent Fixed-Bed Reactor System
High-Yield AAV Viral Vector Production in Corning Ascent Fixed-Bed Reactor System
Aug 27, 2021
byZara Melkoumian
eBook: Bioreactor Sensors &mdash;<br> Inside the Dynamics of Cell Culture
PAT
eBook: Bioreactor Sensors — Inside the Dynamics of Cell Culture
eBook: Bioreactor Sensors — Inside the Dynamics of Cell Culture
Apr 30, 2021
byJim Kling
Rapid Development of Viral Vector Production Processes: Iterative Parameter Optimization
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Rapid Development of Viral Vector Production Processes: Iterative Parameter Optimization
Rapid Development of Viral Vector Production Processes: Iterative Parameter Optimization
Apr 16, 2021
+1
byJakub Krakowiak, Qian Liuand 1 more
Bioreactor Automation Driven by Real-Time Sensing: Enhancing Productivity Through Accurate, Efficient Glucose Control
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Bioreactor Automation Driven by Real-Time Sensing: Enhancing Productivity Through Accurate, Efficient Glucose Control
Bioreactor Automation Driven by Real-Time Sensing: Enhancing Productivity Through Accurate, Efficient Glucose Control
Feb 4, 2021
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byHiroaki Yamanaka, Yasuhito Muratoand 1 more
Updating the Economics of Biologics Manufacturing with 5,000-L Single-Use Bioreactors: A Paradigm Shift
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Updating the Economics of Biologics Manufacturing with 5,000-L Single-Use Bioreactors: A Paradigm Shift
Updating the Economics of Biologics Manufacturing with 5,000-L Single-Use Bioreactors: A Paradigm Shift
Oct 9, 2020
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byMark T. Smith, Levi Morin Larsenand 2 more
Dissolved Oxygen Control Tuning for Cell Culture Applications
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Dissolved Oxygen Control Tuning for Cell Culture Applications
Dissolved Oxygen Control Tuning for Cell Culture Applications
Sep 22, 2020
+1
byJohn Longsworth, Nina Schillingsand 1 more
Retrofitting Your Bioreactor to Enhance Stirring Processes: Replacing Old Agitators with State-of-the-Art Magnetic Mixing Technology
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Retrofitting Your Bioreactor to Enhance Stirring Processes: Replacing Old Agitators with State-of-the-Art Magnetic Mixing Technology
Retrofitting Your Bioreactor to Enhance Stirring Processes: Replacing Old Agitators with State-of-the-Art Magnetic Mixing Technology
Jun 10, 2020
byNicole Zangl
A Rapid, Low-Risk Approach Process Transfer of Biologics from Development to Manufacturing Scale
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A Rapid, Low-Risk Approach Process Transfer of Biologics from Development to Manufacturing Scale
A Rapid, Low-Risk Approach Process Transfer of Biologics from Development to Manufacturing Scale
May 24, 2020
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bySebastian Ruhl, Naomi de Almeidaand 4 more
Navigating Technology Transfer
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Navigating Technology Transfer
Navigating Technology Transfer
May 20, 2020
byMarie-Laure Collignon, Shahin Heshmatifar
Industrialize Your Viral Vector Production in Adherent and Suspension Cell Cultures: Know the Pros and Cons
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Industrialize Your Viral Vector Production in Adherent and Suspension Cell Cultures: Know the Pros and Cons
Industrialize Your Viral Vector Production in Adherent and Suspension Cell Cultures: Know the Pros and Cons
May 11, 2020
byEmmanuelle Cameau, Joseph Capone
Matrix: The Highly Automated Multibioreactor Solution That Fits to Your Bench Space, Bioprocessing Needs, and Budget
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Matrix: The Highly Automated Multibioreactor Solution That Fits to Your Bench Space, Bioprocessing Needs, and Budget
Matrix: The Highly Automated Multibioreactor Solution That Fits to Your Bench Space, Bioprocessing Needs, and Budget
Dec 10, 2019
byTom van Arragon, Matthijs Neimeijer
From Supplying Components to Providing Total Solutions: Overviewing Supplier Side Capabilities
Supply Chain
From Supplying Components to Providing Total Solutions: Overviewing Supplier Side Capabilities
From Supplying Components to Providing Total Solutions: Overviewing Supplier Side Capabilities
Oct 28, 2019
byPhilip Cherian
Production of Transient Lentiviral Vectors in HEK 293T Cells: Cultivation on Fibra-Cel Disks in a Single-Use, Packed-Bed, Stirred-Tank Bioreactor
Sponsored Content
Production of Transient Lentiviral Vectors in HEK 293T Cells: Cultivation on Fibra-Cel Disks in a Single-Use, Packed-Bed, Stirred-Tank Bioreactor
Production of Transient Lentiviral Vectors in HEK 293T Cells: Cultivation on Fibra-Cel Disks in a Single-Use, Packed-Bed, Stirred-Tank Bioreactor
Oct 23, 2019
byDavid Solbach

Webinars

Ask the Expert webcasts
ATE Webcasts
Register Now: Big Impact from Small Samples: Harnessing High-Precision Tunable Laser Spectroscopy for Complex Bioprocessing Analysis
Register Now: Big Impact from Small Samples: Harnessing High-Precision Tunable Laser Spectroscopy for Complex Bioprocessing Analysis
Ask the Expert webcasts
ATE Webcasts
Register Now: Advancing mRNA and CircRNA-based Vaccines and Therapeutics in CMC: From Process Development to Analytics
Register Now: Advancing mRNA and CircRNA-based Vaccines and Therapeutics in CMC: From Process Development to Analytics
Insider News
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Jun 5 - Jun 6, 2024
Exploit Advances in Exosomes to Improve Efficiencies in Drug Delivery: Connect with senior-level executives and scientists who will share new data and novel case studies on advancing EV products through clinical stage towards commercialization
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Innovative Technology

Bruker Tornado Spectroscopy
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Monitoring and Controlling Upstream Bioprocesses with Raman Spectroscopy
Monitoring and Controlling Upstream Bioprocesses with Raman Spectroscopy

Dec 1, 2024

Thermo Fisher White Paper
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Peptones: A Powerful Tool for Manufacturing Complex Protein Therapies
Peptones: A Powerful Tool for Manufacturing Complex Protein Therapies

Nov 21, 2024

Thermo Fisher WP
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Efficient-Pro Medium and Feed 1 Enable Rapid and Seamless Upstream Process Development and Scale-Up for CHO-K1 Cells
Efficient-Pro Medium and Feed 1 Enable Rapid and Seamless Upstream Process Development and Scale-Up for CHO-K1 Cells

Nov 21, 2024

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