Integrity™ 2-D and 3-D Bioprocess Vessels

Richard Bhella

July 1, 2010

2 Min Read


Efficient movement and storage of liquids is critical to modern biotechnology processes. The deployment of single-use containers for this task has become ubiquitous in recent years because they reduce risk while driving down costs in comparison with traditional stainless steel equipment

ATMI’s integrity 2-d and 3-d Bioprocess vessel (BPV) products have been developed to meet the demand for cost-effective, scalable, single-use liquid storage containers that are compatible with ATMI’s market-leading range of single-use mixing and bioreactor technologies.

At the heart of ATMI’s Integrity systems and products is integrity TK8 film, a state-of-the-art multilayer gas-barrier polymer laminate. The product-contacting layer of TK8 film is blow extruded in-house by ATMI under cleanroom conditions using medical-grade ultralow-density polyethylene resin, then laminated to create a gas barrier film of exceptional cleanliness, strength, and clarity that is animal-derived component free (ADCF) and complies fully with USP Class VI requirements.

TK8 film is standard across the ATMI integrity product lines, providing users with easy scalability and simplified cross-platform validation.


  • State-of-the-art designs and materials

  • Manufactured on automated equipment under ISO Class 5 (Class 100) cleanroom conditions

  • Suitable for virtually any storage application

  • Standard and custom configurations available

  • Integrity tested using ATMI’s advanced whole-bag testing technology.

  • “Universal” TK8 bioprocess film


Scalable And Configurable

Standard 3-D BPV sizes range from 100 to 1,000 L, and standard 2-D BPV sizes range from 1 to 50 L. Integrity BPV products are consistent with industry dimensional norms. Tubing connections are made via a molded fitment sealed into the BPV. Broad connectivity options exist, with tubing sizes from 1/8” to 1” as standard. Specialty components such as sterile connectors and filters are available upon request. To discuss your specific needs, contact your ATMI representative.

© 2010 ATMI, Inc. All rights reserved. ATMI, the ATMI logo and Integrity are trademarks or registered trademarks of Advanced Technology Materials, Inc. in the U.S., other countries, or both. All other names are the property of their respective owners.

About the Author

Author Details
Richard Bhella is the global product manager, Single-Use Storage and Delivery Technologies, at ATMI, 2151 E Broadway Road #101, Tempe, AZ 85282; 1-800-966-6698; [email protected].

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