Investigation of Hitchhiking Impurities Removed by the 3M EMPHAZE AEX Hybrid Purifier

BPI Contributor

October 8, 2019

20 Min View
Investigation of Hitchhiking Impurities Removed by the 3M EMPHAZE AEX Hybrid Purifier

Date: Oct 8, 2019

Duration: 20 Min

This webcast is hosted by: Dr. Hani El-Sabbahy, Biopharmaceutical Application Engineering Specialist, Separation and Purification Sciences Division, 3M United Kingdom PLC

3M™ Emphaze™ AEX Hybrid Purifier is an all-synthetic clarifier consisting of a high capacity Q-functional hydrogel and a 0.2 μm polyamide membrane. The open structure and high charge capacity can handle turbid feeds, resulting in soluble and insoluble contaminant removal.

Using data generated by sophisticated LC-MS/MS techniques, this webinar will explore the impact of deploying the Emphaze AEX Hybrid Purifier as a polishing clarification step on specific problematic host cell protein (HCP) contaminants. The data presented will focus on tracking these problematic HCPs through clarification and protein A chromatography.

Contains research data from studies conducted at NIBRT, Ireland.

Watch the recorded webcast below.

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