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Improved Single-Use Technology for Online Turbidity Measurements

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Figure 1: Turbidity system setup

Turbidity is the relative clarity of a liquid as the result of suspended solids. Typically, turbidity measurements are taken by using a beam of light to detect the presence of particles and measuring the difference between the amount of light that is emitted from a source and the amount received by a detector. In bioprocess operations, liquid turbidity often is measured postfiltration to detect “break through,” or undesired materials coming from a filter, which provides an overall assessment of filter performance.

Presently, turbidity measurements are made through offline sampling. However, that approach is inefficient and often disrupts bioprocesses. By contrast, PendoTECH’s
single-use turbidity measurement system takes on-line measurements, enabling users to monitor turbidity in real time. The system uses single-use flow cells, which enable users to take noninvasive measurements (no physical product contact), and it eliminates the need for typical maintenance requirements such as calibration and cleaning.

Fill out the form below to read the complete technology review and learn more about single-use flow cells now.

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