A Scalable Single-Use Two-Step Plasmid Purification Process

BPI Contributor

November 3, 2023

20 Min View
A Scalable Single-Use Two-Step Plasmid Purification Process

Date: Nov 3, 2023

Duration: 20 Min

This webcast features: Simon Åberg, Senior Research Engineer, Cytiva.

The current global demand for biopharmaceuticals is over USD 300 billion, with an estimated growth of ≥ 12% annually. While MAb processes have become much more efficient, production of mRNA and viral vectors is still hindered by the requirement for a reliable source of high-quality plasmid DNA (pDNA), which typically requires multiple purification steps to achieve.

In this webinar, Cytiva will describe a scalable purification process that produces clinical-grade pDNA (>80% supercoiled pDNA) in just two steps.

Key Takeaways:

  • How to purify GMP-grade pDNA in a two-step chromatography process.

  • When to use membrane chromatography as a capture step.

  • A quick and easy way to analyze pDNA quantity and quality.

Just fill out the form below to watch the recorded webcast now.

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