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Purification of Clinical Grade MAb using Hydrophobic Cation Exchange Chromatography Resin
1 Min Read
Sponsored by Bio-Rad
A three-step non-rProtein A capture process shows how the selectivity afforded by Nuvia cPrime resin can be used to clear a light chain contaminant that has a homologous sequence and similar pI to the target MAb monomer.
The unique balance between the hydrophobic and charged character of Nuvia cPrime allows for a compact process with reduced buffer consumption and feed conditioning.
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