This special report from Sartorius Stedim Biotech explores recent advances in single-use process platforms for commercial production of biopharmaceuticals. Enormous developments have been made in single-use systems, allowing biomanufacturers to adopt the technology in critical applications within their commercial-scale facilities. The authors illustrate how companies can work with teams of experts from supplier organizations to implement end-to-end single-use bioprocesses at scales up to 2,000 L by carefully considering the approach from the earliest stages in process development. Finally, the report examines how cutting-edge developments in sensors and data analysis methods give biomanufacturers significantly improved control of their bioprocesses than they have ever experienced before. Each expert contributor presented on his or her respective topic to audiences at the Biotech Week Boston conference in 2017.

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