A Scalable Immobilized Metal Affinity Chromatography Resin for Process Purification

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A Scalable Immobilized Metal Affinity Chromatography Resin for Process PurificationDownstream process purification of proteins requires a resin with optimized bead size for ideal pressure/flow properties and decent dynamic binding capacity (DBC) that provides production efficiencies and good process economics. Our newly developed metal chelate affinity resin — Nuvia™ IMAC — provides the mechanical strength, pore structures, ligand density, and particle size distribution required for an operation run at 300 cm/hr with a DBC of >40 mg/ml at

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