Feedback    Advertise    Submit Papers    Reprints    About    Help    Contact   
Upstream Processing Downstream Processing Manufacturing Analytical Facilities
Archive by Issue Archive by Article Type Supplements
CMC Forum Press Releases
Integrity™ 2-D and 3-D Bioprocess Vessels
Richard Bhella
BioProcess International, Vol. 8, No. 7, July–August 2010, p. 108
 



Efficient movement and storage of liquids is critical to modern biotechnology processes. The deployment of single-use containers for this task has become ubiquitous in recent years because they reduce risk while driving down costs in comparison with traditional stainless steel equipment

ATMI's integrity 2-d and 3-d Bioprocess vessel (BPV) products have been developed to meet the demand for cost-effective, scalable, single-use liquid storage containers that are compatible with ATMI's market-leading range of single-use mixing and bioreactor technologies.

At the heart of ATMI's Integrity systems and products is integrity TK8 film, a state-of-the-art multilayer gas-barrier polymer laminate. The product-contacting layer of TK8 film is blow extruded in-house by ATMI under cleanroom conditions using medical-grade ultralow-density polyethylene resin, then laminated to create a gas barrier film of exceptional cleanliness, strength, and clarity that is animal-derived component free (ADCF) and complies fully with USP Class VI requirements.

TK8 film is standard across the ATMI integrity product lines, providing users with easy scalability and simplified cross-platform validation.

Highlights

  • State-of-the-art designs and materials

  • Manufactured on automated equipment under ISO Class 5 (Class 100) cleanroom conditions

  • Suitable for virtually any storage application

  • Standard and custom configurations available

  • Integrity tested using ATMI's advanced whole-bag testing technology.

  • “Universal” TK8 bioprocess film



Scalable And Configurable

Standard 3-D BPV sizes range from 100 to 1,000 L, and standard 2-D BPV sizes range from 1 to 50 L. Integrity BPV products are consistent with industry dimensional norms. Tubing connections are made via a molded fitment sealed into the BPV. Broad connectivity options exist, with tubing sizes from 1/8” to 1” as standard. Specialty components such as sterile connectors and filters are available upon request. To discuss your specific needs, contact your ATMI representative.

© 2010 ATMI, Inc. All rights reserved. ATMI, the ATMI logo and Integrity are trademarks or registered trademarks of Advanced Technology Materials, Inc. in the U.S., other countries, or both. All other names are the property of their respective owners.

Author Details
Richard Bhella is the global product manager, Single-Use Storage and Delivery Technologies, at ATMI, 2151 E Broadway Road #101, Tempe, AZ 85282; 1-800-966-6698; rbhella@atmi.com.

 
| | Share
Biopharmaceutical Production
Facility Design Strategies for Single-Use Technologies

Please join us for a free webinar addressing strategies for facility design in biopharmaceutical manufacturing:

Wednesday, 29 February 2012
8:00 AM and 1:00 PM EST

Presented by:

Ingrid Long, MSc
Research Engineer
GE Healthcare Life Sciences

Register today!

During the webinar, Ms. Long will discuss the impact of different strategies for facility design, with a focus on the following topics:

* Replacement of traditional equipment with the single-use equivalent
* Biopharmaceutical manufacturing in a single room
* Benefits of facility design with respect to cost, risk, and flexibility

Register today!


Nine Conferences — One Location: Hilton Bayfront (San Diego, CA)
Webinars   
Subscribe   
Reprints   
Contact   
About   
Informa plc
©2002 - 2009 BioProcess International
Ph: 508-616-5550