Small-Scale Fluid Control

Product: Flipper 6650 solenoid valve

Applications: Analytical fluid dosing

Features: With a pitch of only 4.5 mm, the Flipper 6650 solenoid valve comes in 2/2- and 3/2-way versions that offer performance comparable to 10-mm and 16-mm valves. The media-separated valve is compact and fast-switching, optimized especially for reproducible and precise dosing of aggressive fluids. Because of its compact size, the valve requires smaller internal volume in the connecting plates, thus increasing efficiency of media use, which can significantly reduce costs.

Contact Bürkert Fluid Control Systems

www.burkert.com

Single-Use Tubing

Literature: One-Touch Fluid Path Assemblies brochure

Features: One-Touch single-use fluid path assemblies are highlighted in detail in a brochure from Meissner. It illustrates common process configurations that use the company's library of prequalified components. Additionally, fluid path assemblies are shown with attached capsule filters for filtration of volumes from 10 mL to >10,000 L. Data on gamma irradiation are also covered. One-Touch assemblies can be customized to end-user requirements and include dynamic combinations of connectivity, tubing, and other components to achieve the functionality necessary for process demands.

Contact Meissner Filtration Products

www.meissner.com

Cell Culture Development

Product: Telstar Hexacreen system

Applications: Cell culture screening

Features: Telstar's miniature bioreactor can enable 10 − 15 animal cell culture trials and experiments and handle six cultures at a time. These units offer change of medium, monitoring, and control facilities similar to laboratory reactors. They enable the collection of information on major culture variables such as temperature, dissolved oxygen and/or oxygen consumption, pH, optical density, and spectrum measurement in the visible range. The system simultaneously monitors growth (absorbance) and metabolism (indirectly from acidification/oxygen consumption).

Contact Telstar

www.telstar.eu

Clinical Development

Product: qPCR integration assay

Applications: Plasmid DNA integration

Features: When a plasmid construct is selected for clinical development, the FDA requires that a study be conducted to confirm that plasmid DNA integration is either absent or insignificant. A key factor in this determination is the limit of detection for the assay used. AltheaDx's qPCR integration assay measures ≥5 copies of plasmid DNA per microgram of genomic DNA. The sensitivity and specificity of this assay make it well suited to integration studies. The company's scientists will work closely with yours to design a signature assay customized to your specific needs.

Contact AltheaDx

www.altheadx.com/platforms/integration.php

Disposable Bioreactor

Product: Parallel Bioreactor System control and CellReady 3L

Applications: Benchtop cultures

Features: The Mobius CellReady 3L single-use bioreactor can be integrated into DASGIP's control system using its Parallel Bioreactor System concept. This combines familiar process control with the advantages of single-use technology. A disposable bioreactor eliminates the need to clean and autoclave. Operators can add monitoring and control units as their applications require, including mass-flow − controlled gas mixing, variable-speed controlled pumps, and monitoring of pH and dissolved oxygen. Advanced in-line measurements such as off-gas analysis or optical density monitoring are also possible.

Contact DASGIP

www.dasgip.com