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April 2010

April 2010, Vol.8 No.4

On the Cover

Scanning electron micrograph of Vero cells cultured on microcarrier beads with Thermo Fisher Scientific media. (www.hyclone.com)

Focus On…

COMPLIANCE

Are “Land Mines” Hiding in Your Supplier Records?

John Avellanet

BioProcess International, Vol. 8, No. 4, April 2010, pp. 10–14

FOCUS ON…

Terminology Management

Uwe Muegge, CSOFT International

BioProcess International, Vol. 8, No. 4, April 2010, pp. 16–20

Understanding the Basics of Peptide and Protein Production

Gary Hu

BioProcess International, Vol. 8, No. 4, April 2010, pp. 22–25

BioProcess Technical

An Efficient Thermoinducible Bacterial Suicide System

Shingo Tsuji, Ilham Naili, Nathan R. Authement, Anca M. Segall, Veronica Hernandez, Bryan M. Hancock, Matthew J. Giacalone, Stanley R. Maloy

BioProcess International, Vol. 8, No. 4, April 2010, pp. 28–40

Changes in Raw Material Sources from Suppliers

Alejandro Toro, Janet Colon, Victor Melendez-Colon, Jose Hector Rivera

BioProcess International, Vol. 8, No. 4, April 2010, pp. 50–55

How Pore and Fibrous Interstice Structure Influence Filter Performance

Russell E. Madsen, Theodore H. Meltzer, Maik W. Jornitz

BioProcess International, Vol. 8, No. 4, April 2010, pp. 58–64

Bioprocess Technical

Is Bovine Albumin Too Complex to Be Just a Commodity?

Frank J. Mannuzza, Joseph G. Montalto

BioProcess International, Vol. 8, No. 4, April 2010, pp. 42–48

Vendor Voice

Isolation of Novel High-Osmolarity Resistant CHO DG44 Cells After Suspension of DNA Mismatch Repair

Xiaoguang Liu, Jian Liu, Tasha Williams Wright, Jessica Lee, Peggy Lio, Laurel Donahue-Hjelle, Paula Ravnikar, Florence Wu

BioProcess International, Vol. 8, No. 4, April 2010, pp. 68–76

Global Marketplace

BioProcess International, Vol. 8, No. 4, April 2010, pp. 78–80

Global Meetingplace

Cell Line Development and Engineering Novel Approaches to Improve Speed of Development, Stability, Manufacturability, Quality, and Fundamental Understanding

BioProcess International, Vol. 8, No. 4, April 2010, p. 82

Elucidation

Making a Positive Urban Impact

Tom Harvath

BioProcess International, Vol. 8, No. 4, April 2010, p. 84

The Best of GE Healthcare: Tools for vaccine processes

In vaccine development and manufacturing, GE Healthcare provides a suite of scalable solutions from cell culture through purification to analysis, which offer flexibility and economy, improve purity and secure quality.

Microcarriers and disposable bioreactors for MDCK and Vero cell culture
Secure cell propagation with adherent cells at reduced cost and with increased flexibility

DNA removal from influenza virus culture
HTPD and DoE for development and optimization of a chromatography step for the removal of host cell derived genomic DNA

Editors' Blog

On the (BPI) Road (Part 2)

More Travel Tips from the Editor in Chief

Practical Considerations for DoE Implementation in Quality By Design

BioProcess International Conference & Exhibition

Contractor Responsibilities in Outsourced Pharmaceutical Quality Control Testing

Measuring Manufacturing Cost and Its Impact on Organizations

Fluorescence-Activated Cell Sorting for CGMP Processing of Therapeutic Cells

I'm Losing Cell Viability and Function at Different Points in My Process, and I Don't Know Why!

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