News

Tosoh Bioscience Introduces TOYOPEARL® AF-rProtein L-650F Process Chromatography Resin

Tosoh Bioscience LLC, a provider of chromatographic resins for the purification of biopharmaceutical drugs in commercial manufacturing processes, today announced the introduction of TOYOPEARL AF-rProtein L-650F, a Protein L resin that exhibits the highest binding capacity for antibody fragments that lack a Fc-portion (e.g. Fab, ScF Dab, etc.). TOYOPEARL AF-rProtein L-650F resin is now available for sale in the Americas from Tosoh Bioscience LLC. TOYOPEARL AF-rProtein L-650F resin does not only offer the highest binding capacity, but also has the…

MilliporeSigma’s Integritest® 5 Instrument Provides Integrity Testing, Assurance

MilliporeSigma’s new Integritest® 5 instrument is an easy-to-use, portable and fully automated integrity test system for verification of filters and processing equipment. The latest model of the first commercially available automated integrity test instrument introduced more than 25 years ago now incorporates an improved algorithm to simplify test creation and accelerate test completion. The user-friendly software makes it easy to set up and manage users and tests, while offering a depth of advanced functionality for those who need additional options.…

Sanofi and Lonza Enter into a Strategic Partnership to Establish a Large-Scale Biologics Production Facility

Sanofi and Lonza announced today that they have entered into a strategic partnership to build and operate a large-scale mammalian cell culture facility for monoclonal antibody production in Visp, Switzerland. The strategic partnership in the form of a joint venture combines the strong biologics development pipeline of Sanofi with the expertise of Lonza to design, construct, start-up and operate a state-of-the-art large-scale mammalian cell culture facility. The initial investment will be around CHF 290 million (€ 270 million), to be…

Distek, Inc. Releases Eclipse 5300 Automated Dissolution Sampler

Distek, Inc., a leading manufacturer of laboratory testing instruments for the pharmaceutical and biotechnology industry, as well as an experienced provider of validation and qualification services, announced today the release of the Eclipse 5300 automated dissolution sampler. The Eclipse 5300 Automated Dissolution Sampler by Distek offers rapid and accurate sampling using precision syringes. The elimination of valves and rotary pumps along with the short sample pathway and minimal dead volume increases reliability while eliminating and reducing common sources of sample…

Lonza and Selecta Biosciences Announce Manufacturing Agreement for Anc80-AAV-Based Gene Therapy for Treatment of Methylmalonic Acidemia

Lonza Houston, Inc., a global leader in viral gene and cell therapy manufacturing, and Selecta Biosciences, Inc., a clinical-stage biopharmaceutical company focused on developing biologic therapies for rare and serious diseases that avoid unwanted immunogenicity, have entered into a strategic manufacturing agreement. Under the terms of the agreement, Lonza will produce an Anc80-AAV-based gene therapy product for Selecta’s proprietary program for the treatment of Methylmalonic Acidemia (MMA), a rare inborn error of metabolism, and may in the future produce other…

Almatec® Featuring BIOCOR Series Pumps at INTERPHEX 2017

Almatec®, part of PSG®, a Dover company and premier manufacturer of sanitary air-operated double-diaphragm (AODD) pumps, will be featuring its BIOCOR Series pumps for sterile applications in Booth 2253 at INTERPHEX 2017. The INTERPHEX event brings together a wide variety of leaders from the pharmaceutical and biotech industries and will be held at the Jacob K. Javits Convention Center in New York, NY, USA, from March 21-23. BIOCOR pumps from Almatec have been specifically designed for critical biotech and pharmaceutical…

Rentschler and Leukocare Announce Formulations Strategic Alliance and Equity Investment

Rentschler Biotechnologie GmbH, Laupheim and Leukocare AG, Martinsried today announced a strategic alliance under which Leukocare will become the specialized technology partner and the exclusive formulation developer for Rentschler’s biopharmaceuticals business. Rentschler in return will become the first and only contract development and manufacturing organization (CDMO) to have access to Leukocare´s patented SPS® formulation technologies. Leukocare’s ongoing and future business activities with pharma and biotech beyond the CDMO business will not be affected by this alliance. Rentschler will acquire a…

Servier Appoints MaSTherCell for the Development of its CAR-T Cell Therapy Manufacturing Platform

Servier, the independent international pharmaceutical company, and MaSTherCell SA, the full-service contract development and manufacturing organization (CDMO) specializing in the delivery of optimized process industrialization capacities to cell therapy organizations, today announced the signing of a master service agreement for the development of a manufacturing platform for allogeneic cell therapies. Under the master service agreement, MaSTherCell is developing a CAR-T cell therapy manufacturing platform, which will enable industrial and commercial manufacturing of Servier cell therapy products. This is a critical…

Vetter Starts Operations in its Center for Visual Inspection and Logistics

Vetter, a leading global Contract Development and Manufacturing Organization (CDMO) for development, aseptic filling and final packaging of injectables, has announced today that it has begun operations in its expanded Visual Inspection and Logics Center located in Ravensburg. The enlargement, in which the company invested approximately 100 million euros ($107 million), bundles capacity for final product inspection and logistics in one cutting-edge site. By finalizing the second construction stage of the site that was initially put into operation five years…

MilliporeSigma Launches First Commercial Service to Predict Multiple Sources of DNA Damage

MilliporeSigma has introduced CAN MultiFlow™ screening services to more accurately predict genotoxic and mode of action* properties of substances, ingredients and drug compounds. Offered through its BioReliance® testing facilities, MilliporeSigma will be the first company to provide this service in the United States. The screening process uses flow cytometry to quickly and efficiently screen for clastogens, aneugens and non-genotoxicants (CAN) in pharmaceutical compounds, agricultural chemicals, flavors, fragrances and consumer products. The results from the assay can help manufacturers reject harmful…