News

Vetter and Microdermics Enter into a Strategic Cooperation Agreement to Develop Innovative Microneedle Drug Delivery Systems

Vetter, a leading and innovative provider of aseptic prefilled drug delivery systems and Microdermics Inc., a Vancouver-based medical device company developing a novel hollow, metal microneedle drug and vaccine delivery system, today announced that they have entered into a strategic cooperation agreement. The market in novel alternatives to needle injections is forecasted to grow rapidly, reaching in excess of 480 million units by 2030 (Roots Analysis report). Microneedles are a novel technology that can offer promising advantages as an alternative…

Lonza Acquires Cell and Gene Contract Manufacturer PharmaCell

On 3 May 2017, Lonza successfully completed the acquisition of PharmaCell B.V., one of the most-respected cell and gene contract manufacturers in Europe with employees in Maastricht and Geleen (NL). In 2016 PharmaCell had sales of EUR 11 million. PharmaCell was primarily selected due to its core expertise in autologous cell and gene therapy manufacturing, which includes experience with two commercial Advanced Therapy Medicinal Products (ATMPs)-licensed products. Autologous therapies use a patient’s own cells. “PharmaCell’s position in the market complements…

Quantum Redefines Peristaltic Pump Performance for Single-Use Downstream Bioprocessing

Watson-Marlow Fluid Technology Group (WMFTG) has unveiled its innovative Quantum peristaltic pump with patented ReNu single-use (SU) cartridge technology. Engineered by the world leader in peristaltic innovation, Quantum sets the new standard for high-pressure feed pumps in SU tangential flow filtration (TFF), virus filtration (VF) and high-performance liquid chromatography (HPLC). Quantum represents a step-change in pump technology for bioprocessing by enabling higher downstream process yields throughout the pressure range, delivering virtually pulse free linear flow, lowest shear and easy validation…

JSR Life Sciences Expands Manufacturing Capabilities at KBI Biopharma

JSR Life Sciences (JLS) today announced that KBI Biopharma (KBI), a subsidiary of JSR Corporation (JSR), is expanding its biopharmaceutical manufacturing capacity and capabilities at both its Durham, North Carolina and Boulder, Colorado facilities. KBI is investing approximately $30M on the two site expansion projects, which will greatly enhance the offerings at each site and are scheduled for completion later this year. KBI is building commercial mammalian cell culture manufacturing capability within its Durham facility, which also houses CGMP cell…

MilliporeSigma Develops Alternative CRISPR Genome Editing Method

MilliporeSigma has developed a new genome editing tool that makes CRISPR more efficient, flexible and specific, giving researchers more experimental options and faster results that can accelerate drug development and access to new therapies. This new technique, called “proxy-CRISPR,” provides access to previously unreachable areas of the genome. Most natural CRISPR systems, found in bacteria, cannot work in human cells without significant re-engineering. However, proxy-CRISPR provides a rapid and simple method to increase their usability without the laborious need to…

May Spotlight

Welcome New Editorial Advisor David Rabuka is global head of research and development in chemical biology at Catalent Biologics, with overall responsibility of overseeing continued research and development of SMARTag technology. He also oversees strategy, resource allocation, and scientific oversight of preclinical and clinical studies. David joined Catalent Biologics following Catalent’s acquisition of Redwood Bioscience Inc., where he was founder, president, and chief scientific officer. David’s scientific areas of expertise include chemical synthesis; drug delivery; translational research; chemistry, manufacturing, and…

Sartorius Stedim Biotech Partners with Nova Biomedical

Sartorius Stedim Biotech (SSB), a leading international supplier to the biopharmaceutical industry, today announced an agreement with Nova Biomedical (Nova), a well-known US manufacturer of cell culture analyzers, to integrate their BioProfile® FLEX2 into the ambr® multi-parallel bioreactor systems for automated, at-line cell culture analytics. SSB and Nova are collaborating to combine two highly innovative technologies. Both the BioProfile® FLEX2 analyzer and the parallel bioprocessing functionality of the ambr® create a unique tool able to simultaneously run, sample and analyze…

MilliporeSigma Launches Industry’s First Off-the-Shelf Cell Culture Media for Perfusion Processes

MilliporeSigma, today took a significant step toward increasing manufacturing flexibility and enabling higher productivity with the launch of the EX-CELL® Advanced™ HD Perfusion Medium. This first off-the-shelf, high-density cell culture media supports perfusion processes and facilitates high productivity at low perfusion rates, increasing production yield and speed to clinic. Biomanufacturers are moving toward perfusion processes, the next generation in manufacturing, as they seek to cut costs while increasing quality and efficiency. Perfusion processes, however, require a new type of medium…

JSR Life Sciences Expands Amsphere™ A3 Production Capacity

JSR Life Sciences (JLS), the global life sciences focused division of JSR Corporation, today announced plans for expansion of its production capabilities of Amsphere™ A3 protein-A chromatography resin at JSR’s Belgium subsidiary, JSR Micro NV. This expansion will effectively increase its production capacity by six times and provide redundancy in its manufacturing capability. JLS’s Amsphere™ A3 has experienced rapid adoption as an alkali-stable, high-capacity alternative option for downstream purification in the biopharmaceutical industry since its launch in January 2016. Based…

Sartorius Stedim Biotech Introduces New BIOSTAT STR® Bioreactor Range

Sartorius Stedim Biotech (SSB), a leading international supplier for the biopharmaceutical industry, announced the launch of its next generation BIOSTAT STR®, a fully scalable, single-use bioreactor family based on a conventional stirred-tank design. This new bioreactor range featuring upgraded hardware and software, as well as a fully integrated, new design of Flexsafe STR® single-use bags, ensures quick and easy bioprocess scale-up of biologics and vaccines. The BIOSTAT STR® bioreactors are equipped with an improved stainless steel bag holder for user…