Monday September 25, 2017
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Covering the whole development process for the global biotechnology industry
Bioprocessing begins upstream, most often with culturing of animal or microbial cells in a range of vessel types (such as bags or stirred tanks) using different controlled feeding, aerating, and process strategies.
Cell Culture Media
Perfusion Cell Culture
Upstream Contract Services
Upstream Single-Use Technologies
Beginning with harvest of material from a bioreactor, downstream processing removes or reduces contaminants to acceptable levels through several steps that typically include centrifugation, filtration, and/or chromatographic technologies.
Downstream Contract Services
Downstream Single-Use Technologies
Drug products combine active pharmaceutical ingredients with excipients in a final formulation for delivery to patients in liquid or lyophilized (freeze-dried) packaged forms — with the latter requiring reconstitution in the clinical setting.
Manufacturing Contract Services
Many technologies are used to characterize biological products, manufacturing processes, and raw materials. The number of options and applications is growing every day — with quality by design (QbD) giving impetus to this expansion.
Even as it matures, the biopharmaceutical industry is still a highly entrepreneurial one. Partnerships of many kinds — from outsourcing to licensing agreements to consultancies — help companies navigate this increasingly global business environment.
Pre-Clinical and Clinical Trials
October 2004 Supplement
A Disposable Option for Bovine Serum Filtration and Packaging
A Technology On The Rise
Biomanufacturing for the 21st Century
Considerations for Use of Disposable Technology in Contract Manufacturing
Crossflow Filters Enter the Disposables Arena
Disposable Assemblies in Biopharmaceutical Production
Disposable Technology for Controlled Freeze–Thaw
Integrating Single-Use Disposable Processes into Critical Aseptic Processing Operations
Production-Scale Disposable Filtration in Biomanufacturing