Thursday, September 8, 2016 Daily Archives

Distek, Inc. Releases Opt-Diss 410 In-Situ UV Fiber Optic System for Dissolution Testing

Distek, Inc., a leading manufacturer of laboratory testing instruments for the pharmaceutical and biotechnology industry, as well as an experienced provider of validation and qualification services, announced today the release of the Opt-Diss 410 next generation in-situ UV fiber optic system for dissolution testing. No more sampling! The Distek Opt-Diss 410 UV fiber optic system for dissolution testing measures directly in the vessel, eliminating problematic filters, tubing and pumps used in conventional sampling. Patented ARCH probes designed specifically for dissolution…

Acceleration of Bioprocess Development Using DoE and Physiological Control

This webcast features: Professor Christoph Herwig, Department of Biochemical Engineering, Vienna University of Technology Bioprocess Development for biotechnological high value added products is still a time consuming task. The reason for this is the high complexity of interdependence between process variables, product quality attributes and process parameters. The demonstration of understanding these interdependencies is however key to achieve regulatory acceptance according to Quality by Design (QbD) principles. Hence, it is important to set up senseful experiments and to gather as…

MilliporeSigma Launches New Gene Editing Technology to Engineer Virus Resistant CHO Cell Lines

MilliporeSigma today launched a first-of-its-kind gene editing technology to modify CHO cell lines to be resistant to minute virus of mice (MVM), a common contamination threat that remains despite the shift to chemically-defined, animal component-free manufacturing processes. CHO cells are commonly used in the manufacture of biologics. MilliporeSigma’s new Centinel™ technology targets genes which play a role in MVM susceptibility. Viral contaminations like MVM can have major consequences for biopharmaceutical manufacturers, costing hundreds of millions of dollars, according to industry…